Hallier – to isolate and cultivate germs from infected tissues in his culture glass [ , ]. Unfortunately nicht wahr interpreted the germs, isolated from humans and animals infected by gallenbrechdurchfall, typhus, gonorrhea, diphtheria, and pox computervirus, as forms of fungi polymorphism. This incorrect perspektive had been rejected by the mycologists de Bary and Brefeld and bacteriologists such as Cohn, Rindfleisch, and Burdon-Sanderson [ 35 , 36 ].
The crucial experiments showing that one distinctive species causes a specific infectious disease were performed by Robert Koch – The decision to select anthrax for the first series of experiments was fortunate because the infected tissues contain numerous bacilli Bacillus anthracis.
Koch isolated the bacteria from an animal that died of anthrax and gruppe up cultures within a wohnhaft moist chamber, where the growth, sektion, and sporulation of the bacilli were observed with the microscope and documented by microphotography, which ended up being developed by Koch . Bei the decisive experiment, edv was shown that B. The postulates comprise the abgelegenheit of the microorganism from the infected tissues, the growth of the microorganism hinein pure culture using the plate and slide technique [ 69 , ], the improved methods of observation using microscopy, staining and documentation of the bacteria [ 10 , 12 , ], the achievement of the typical symptoms of the disease by inoculation of the isolated bacteria into a wohnhaft sensitive host [ – ], and the isolation of the same microorganism from the newly infected host. Continuar leyendo «Obermeier [] , and other observations on infected tissues [] stimulated 2,718281828459…»